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Arid3atm1Pwt
Targeted Allele Detail
Summary
Symbol: Arid3atm1Pwt
Name: AT-rich interaction domain 3A; targeted mutation 1, Philip W Tucker
MGI ID: MGI:4941793
Gene: Arid3a  Location: Chr10:79762877-79790852 bp, + strand  Genetic Position: Chr10, 39.72 cM
Alliance: Arid3atm1Pwt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197237
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 through 7 were replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR on fetal liver and adult splenic B cells. (J:169178)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 61 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arid3a Mutation:  20 strains or lines available
References
Original:  J:197237 An G, et al., Loss of Bright/ARID3a function promotes developmental plasticity. Stem Cells. 2010 Sep;28(9):1560-7
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory