Gt(ROSA)26Sortm3(myc*S62A)Rcse
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm3(myc*S62A)Rcse |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Rosalie C Sears |
MGI ID: |
MGI:4941058 |
Synonyms: |
RFS-mycS62A |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm3(myc*S62A)Rcse page
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Germline Transmission: |
Earliest citation of germline transmission:
J:169403
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence) |
Mutation: |
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Insertion
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Gt(ROSA)26Sortm3(myc*S62A)Rcse expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Note |
mouse |
Myc (MGI:97250) |
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Mutation details: A cassette, which contains a floxed neo/STOP cassette and an HA-tagged murine cDNA with phosphorylation mutation that results in the amino acid substitution of alanine for serine at position 62 (T62A), was inserted into the locus.
(J:169403)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gt(ROSA)26Sor Mutation: |
944 strains or lines available
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Original: |
J:169403 Wang X, et al., Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland. Cancer Res. 2011 Feb 1;71(3):925-36 |
All: |
2 reference(s) |
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