Mycntm1(EUCOMM)Wtsi
Targeted Allele Detail
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Symbol: |
Mycntm1(EUCOMM)Wtsi |
Name: |
v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4888950 |
Gene: |
Mycn Location: Chr12:12986094-12991837 bp, - strand Genetic Position: Chr12, 6.14 cM, cytoband A3-B
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IMPC: |
Mycn gene page |
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Mutant Cell Lines: |
EPD0720_1_A04, EPD0720_1_E02, EPD0720_1_E04, EPD0720_1_F03 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 3557 starting at position 12986939 and ending at position 12990496 of Chromosome 12 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
(J:155845, J:173534)
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Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
All: |
2 reference(s) |
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