Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cdc20tm1.1Mama
Name:	cell division cycle 20; targeted mutation 1.1, Marcos Malumbres
MGI ID:	MGI:4887480
Synonyms:	Cdc20lox
Gene:	Cdc20  Location: Chr4:118290098-118294540 bp, - strand  Genetic Position: Chr4, 54.61 cM
Alliance:	Cdc20tm1.1Mama page

Germline Transmission:	Earliest citation of germline transmission: J:167609
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 2, and an FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette leaving exon 2 floxed. (J:167609)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdc20 Mutation:	30 strains or lines available

Original:	J:167609 Manchado E, et al., Targeting mitotic exit leads to tumor regression in vivo: Modulation by Cdk1, Mastl, and the PP2A/B55alpha,delta phosphatase. Cancer Cell. 2010 Dec 14;18(6):641-54
All:	7 reference(s)