Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wlstm1.1Whsu
Name:	wntless WNT ligand secretion mediator; targeted mutation 1.1, Wei Hsu
MGI ID:	MGI:4881718
Synonyms:	Gpr177Fx
Gene:	Wls  Location: Chr3:159545309-159644300 bp, + strand  Genetic Position: Chr3, 82.65 cM
Alliance:	Wlstm1.1Whsu page

Germline Transmission:	Earliest citation of germline transmission: J:167835
Parent Cell Line:	CSL3 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 3 via homologous recombination. Cre mediated recombination removed the neo cassette leaving exon 3 floxed. (J:167835)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	53 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wls Mutation:	38 strains or lines available

Original:	J:167835 Fu J, et al., Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development. Dev Dyn. 2011 Feb;240(2):365-71
All:	17 reference(s)