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Zfp568Gt(RRU161)Byg
Gene trapped Allele Detail
Summary
Symbol: Zfp568Gt(RRU161)Byg
Name: zinc finger protein 568; gene trap RRU161, BayGenomics
MGI ID: MGI:3808700
Synonyms: Zfp568null
Gene: Zfp568  Location: Chr7:29683380-29727707 bp, + strand  Genetic Position: Chr7, 17.26 cM
Alliance: Zfp568Gt(RRU161)Byg page
Mutation
origin
Mutant Cell Line:  RRU161
Germline Transmission:  Earliest citation of germline transmission: J:139139
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation details: A gene trap vector containing neo gene selection cassette was inserted into the Zfp568 gene resulting in abnormal splicing to an acceptor site in the vector insert from the first coding exon of the Zfp568 gene. Fusion protein contains 11 amino acids from Zfp568 followed by 19 amino acids that do not contain any recognizable functional domain. It is a null allele. (J:139139)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Zfp568 Mutation:  128 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:139139 Garcia-Garcia MJ, et al., Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo. Development. 2008 Sep;135(18):3053-62
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory