Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	CrygcChl3
Name:	crystallin, gamma C; chlorambucil, exon 3
MGI ID:	MGI:2176919
Gene:	Crygc  Location: Chr1:65110684-65112691 bp, - strand  Genetic Position: Chr1, 32.81 cM
Alliance:	CrygcChl3 page

Strain of Origin:

(102/El x C3H/El)

Allele Type:    Chemically induced (other) Mutation:    Intragenic deletion   Mutation details: A 6 bp deletion in exon 3 is causative for the cataract phenotype in this mouse. The deletion leads to the loss of two amino acids, Gly and Arg, in the fourth Greek-key motif. (J:73804) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crygc Mutation:	13 strains or lines available

Original:	J:73804 Graw J, et al., A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse. Invest Ophthalmol Vis Sci. 2002 Jan;43(1):236-40
All:	2 reference(s)