Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Symbol:	Tbx4tm1Kng
Name:	T-box 4; targeted mutation 1, David M Kingsley
MGI ID:	MGI:3808009
Synonyms:	Tbx4floxNeoHLEA
Gene:	Tbx4  Location: Chr11:85777248-85806923 bp, + strand  Genetic Position: Chr11, 51.42 cM
Alliance:	Tbx4tm1Kng page

Germline Transmission:	Earliest citation of germline transmission: J:139169
Parent Cell Line:	CGR8 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, Modified regulatory region, No functional change) Mutation:    Insertion   Mutation details: A floxed neo cassette was inserted 5' of the upstream hindlimb enhancer A and an additional loxP site was inserted downstream of it. (J:139169)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx4 Mutation:	23 strains or lines available

Original:	J:139169 Menke DB, et al., Dual hindlimb control elements in the Tbx4 gene and region-specific control of bone size in vertebrate limbs. Development. 2008 Aug;135(15):2543-53
All:	1 reference(s)