Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Col6a1tm1Yah
Name:	collagen, type VI, alpha 1; targeted mutation 1, Yann Herault
MGI ID:	MGI:4868459
Synonyms:	collagen VI null
Gene:	Col6a1  Location: Chr10:76544626-76561878 bp, - strand  Genetic Position: Chr10, 39.71 cM, cytoband B5-C1
Alliance:	Col6a1tm1Yah page

Germline Transmission:	Earliest citation of germline transmission: J:167506
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Not Applicable) Mutation:    Insertion   Mutation details: A neomycin selection cassette, a loxP site and the 5'portion of HPRT were inserted. This allele exists only in cis with Prmt2tm1Yah on chromosome 10. This allele was constructed for the purpose of making the targeted deletions Del(10Prmt2-Col6a1)3Yah. (J:167506)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Col6a1 Mutation:	60 strains or lines available

Original:	J:167506 Besson V, et al., Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses. Hum Mol Genet. 2007 Sep 1;16(17):2040-52
All:	1 reference(s)