Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Prmt2tm1Yah
Name:	protein arginine N-methyltransferase 2; targeted mutation 1, Yann Herault
MGI ID:	MGI:4868409
Gene:	Prmt2  Location: Chr10:76043060-76073699 bp, - strand  Genetic Position: Chr10, 38.74 cM
Alliance:	Prmt2tm1Yah page

Germline Transmission:	Earliest citation of germline transmission: J:167506
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Not Applicable) Mutation:    Insertion   Mutation details: A puromycin selection cassette, a loxP site and the 3'portion of HPRT were inserted between exons 7 and 8. This allele exists only in cis with two other loxP insertions on chromosome 10 (Cstb and Cpl6a1). These alleles were constructed for the purpose of making targeted deletions. (J:167506)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Prmt2 Mutation:	42 strains or lines available

Original:	J:167506 Besson V, et al., Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses. Hum Mol Genet. 2007 Sep 1;16(17):2040-52
All:	3 reference(s)