Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Il23atm1(KOMP)Mbp
Name:	interleukin 23, alpha subunit p19; targeted mutation 1, Mouse Biology Program, UC Davis
MGI ID:	MGI:4867974
Gene:	Il23a  Location: Chr10:128132009-128133953 bp, - strand  Genetic Position: Chr10, 76.51 cM, cytoband D3
IMPC:	Il23a gene page

Mutant Cell Lines:	DEPD00542_2_A01, DEPD00542_2_A03, DEPD00542_2_A04, DEPD00542_2_B01, DEPD00542_2_B03, DEPD00542_2_B04, DEPD00542_2_C01, DEPD00542_2_C02, DEPD00542_2_C03, DEPD00542_2_C04, DEPD00542_2_D01, DEPD00542_2_D02, DEPD00542_2_D03, DEPD00542_2_D04, DEPD00542_2_E01, DEPD00542_2_E02, DEPD00542_2_E03, DEPD00542_2_E04, DEPD00542_2_F01, DEPD00542_2_F03, DEPD00542_2_G01, DEPD00542_2_G02, DEPD00542_2_G03, DEPD00542_2_G04, DEPD00542_2_H02, DEPD00542_2_H03, DEPD00542_2_H04
Germline Transmission:	Unknown
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 929 starting at position 128132602 and ending at position 128133531 of Chromosome 10 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Il23a Mutation:	25 strains or lines available

Original:	J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010;
All:	1 reference(s)