Slc27a4tm1Afst
Targeted Allele Detail
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| Symbol: |
Slc27a4tm1Afst |
| Name: |
solute carrier family 27 (fatty acid transporter), member 4; targeted mutation 1, A Stewart |
| MGI ID: |
MGI:3806116 |
| Synonyms: |
Fatp-4- |
| Gene: |
Slc27a4 Location: Chr2:29692646-29707534 bp, + strand Genetic Position: Chr2, 20.64 cM, cytoband B
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| Alliance: |
Slc27a4tm1Afst page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:138283
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: An Engrailed-2 splice acceptor was fused to the encephalomyocarditis virus internal ribosomal entry site (IRES) and place upstream of a lacZ-neomycin fusion reporter that had been modified by the insertion of a Tn903 promoter between the lacZ and the neo. This was followed by an SV40 polyadenylation signal. This construct was flanked by Frt sites and two loxP sites flank exon 3. This construct was then targeted into intron 2.
(J:138283)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Slc27a4 Mutation: |
36 strains or lines available
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This allele was produced as part of a proof of principle for a targeted gene trap scheme.
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| Original: |
J:138283 Testa G, et al., A reliable lacZ expression reporter cassette for multipurpose, knockout-first alleles. Genesis. 2004 Mar;38(3):151-8 |
| All: |
1 reference(s) |
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Analysis Tools
