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Trpm7tm1e(KOMP)Wtsi
Targeted Allele Detail
Summary
Symbol: Trpm7tm1e(KOMP)Wtsi
Name: transient receptor potential cation channel, subfamily M, member 7; targeted mutation 1e, Wellcome Trust Sanger Institute
MGI ID: MGI:4840971
Gene: Trpm7  Location: Chr2:126633485-126718150 bp, - strand  Genetic Position: Chr2, 61.76 cM, cytoband F2
IMPC: Trpm7 gene page
Mutation
origin
Mutant Cell Lines:  EPD0655_2_A06, EPD0655_2_B05, EPD0655_2_B06, EPD0655_2_B07, EPD0655_2_B08, EPD0655_2_C05, EPD0655_2_C07, EPD0655_2_C08, EPD0655_2_D05, EPD0655_2_D06, EPD0655_2_D08, EPD0655_2_E06, EPD0655_2_F05, EPD0655_2_H05, EPD0655_2_H06
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt0
 
Mutation detailsThe L1L2_gt0 cassette was inserted at position 126692520 of Chromosome 2 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:148605, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Trpm7 Mutation:  98 strains or lines available
References
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory