Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Pdx1-cre)XBMga
Name:	transgene insertion XB, Maureen A Gannon
MGI ID:	MGI:4839475
Synonyms:	Pdx1XBCre
Transgene:	Tg(Pdx1-cre)XBMga  Location: unknown
Alliance:	Tg(Pdx1-cre)XBMga page

Strain of Origin:

(C57BL/6 x DBA/2)F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Pdx1-cre)XBMga expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Pdx1   Mutation details: A 1 kb XhoI-BglII fragment (Pdx1) of the Pdx1 gene fused to the Hsp68 minimal promoter was used to drive expression of a cre recombinase expression cassette. Four founders were generated that displayed similar cre-mediated recombination when crossed to reporter (R26R) mice. (J:72023, J:122333)

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (species not specified) Summary of all recombinase alleles driven by Pdx1.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:122333 Wiebe PO, et al., Ptf1a binds to and activates area III, a highly conserved region of the Pdx1 promoter that mediates early pancreas-wide Pdx1 expression. Mol Cell Biol. 2007 Jun;27(11):4093-104
All:	4 reference(s)