Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nedd4tm2Bros
Name:	neural precursor cell expressed, developmentally down-regulated 4; targeted mutation 2, Nils Brose
MGI ID:	MGI:4836403
Gene:	Nedd4  Location: Chr9:72569628-72657134 bp, + strand  Genetic Position: Chr9, 40.08 cM
Alliance:	Nedd4tm2Bros page

Germline Transmission:	Earliest citation of germline transmission: J:164745
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 7 and 8 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis. (J:164745)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nedd4 Mutation:	116 strains or lines available

Original:	J:164745 Kawabe H, et al., Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron. 2010 Feb 11;65(3):358-72
All:	1 reference(s)