Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Jag2tm2.1Grid
Name:	jagged 2; targeted mutation 2.1, Tom Gridley
MGI ID:	MGI:4829504
Synonyms:	Jag2flox
Gene:	Jag2  Location: Chr12:112871439-112893396 bp, - strand  Genetic Position: Chr12, 61.37 cM
Alliance:	Jag2tm2.1Grid page

Germline Transmission:	Earliest citation of germline transmission: J:163652
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An FRT flanked PGKneo cassette and a distal loxP site were inserted into intron 2 and a second loxP site was inserted about 1.1 kb upstream of the start site via homologous recombination. Flp mediated recombination removed the PGKneo cassette. (J:163652)

In Mice Carrying this Mutation:

37 assay results 1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jag2 Mutation:	44 strains or lines available

Original:	J:163652 Xu J, et al., Generation of mice with a conditional null allele of the Jagged2 gene. Genesis. 2010 Jun;48(6):390-3
All:	8 reference(s)