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Jag2tm2.1Grid
Targeted Allele Detail
Nomenclature
Symbol: Jag2tm2.1Grid
Name: jagged 2; targeted mutation 2.1, Tom Gridley
MGI ID: MGI:4829504
Synonyms: Jag2flox
Gene: Jag2  Location: Chr12:112907819-112929776 bp, - strand  Genetic Position: Chr12, 61.37 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:163652
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT flanked PGKneo cassette and a distal loxP site were inserted into intron 2 and a second loxP site was inserted about 1.1 kb upstream of the start site via homologous recombination. Flp mediated recombination removed the PGKneo cassette. (J:163652)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jag2 Mutation:  26 strains or lines available
References
Original:  J:163652 Xu J, et al., Generation of mice with a conditional null allele of the Jagged2 gene. Genesis. 2010 Jun;48(6):390-3
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory