Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Apptm3.1Umu
Name:	amyloid beta precursor protein; targeted mutation 3.1, Ulrike Muller
MGI ID:	MGI:4822174
Synonyms:	Appflox, Apptm3.1Mull
Gene:	App  Location: Chr16:84751236-84972187 bp, - strand  Genetic Position: Chr16, 46.92 cM, cytoband C3-qter
Alliance:	Apptm3.1Umu page

Germline Transmission:	Earliest citation of germline transmission: J:163059
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed neo resistance cassette was inserted 5' to exon 1 as well as an additional loxP site within intron 1 by homologous recombination. The neo cassette was removed by cre mediated recombination. (J:163059)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any App Mutation:	89 strains or lines available

Original:	J:163059 Mallm JP, et al., Generation of conditional null alleles for APP and APLP2. Genesis. 2010 Mar;48(3):200-6
All:	6 reference(s)