Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Slc6a9tm1.1Veul
Name:	solute carrier family 6 (neurotransmitter transporter, glycine), member 9; targeted mutation 1.1, Volker Eulenburg
MGI ID:	MGI:4818449
Synonyms:	GlyT-
Gene:	Slc6a9  Location: Chr4:117692240-117726502 bp, + strand  Genetic Position: Chr4, 53.62 cM
Alliance:	Slc6a9tm1.1Veul page

Germline Transmission:	Earliest citation of germline transmission: J:161993
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neomycin selection cassette was inserted in intron 2 and a third loxP was inserted in intron 4. The neomycin selection cassette was then removed by transient cre expression leaving exons 3 and 4 floxed. Subsequently, mice were crossed to Tg(EIIa-cre)C5379Lmgd mice to excise exons 3 and 4 creating a knockout allele. (J:161993)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc6a9 Mutation:	24 strains or lines available

Original:	J:161993 Eulenburg V, et al., Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice. Glia. 2010 Jul;58(9):1066-73
All:	1 reference(s)