Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Myctm(Igh-V-EGFP)Janz
Name:	myelocytomatosis oncogene; targeted mutation 1, Siegfried Janz
MGI ID:	MGI:4818379
Synonyms:	iGFP5'Myc
Gene:	Myc  Location: Chr15:61857240-61862223 bp, + strand  Genetic Position: Chr15, 26.19 cM, cytoband D2-D3
Alliance:	Myctm(Igh-V-EGFP)Janz page

Germline Transmission:	Earliest citation of germline transmission: J:162138
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted Mutation:    Insertion   Mutation details: The EGFP gene driven by the immunoglobulin heavy chain variable region (VH) and a floxed neo cassette were inserted 1.5 Kb upstream of the first non-coding exon. The VH-EGFP reporter gene is in the opposite orientation of Myc. This allele serves as a reporter of chromosomal T(12;15) translocation in B lymphocytes and plasma cells. (J:162138)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myc Mutation:	42 strains or lines available

Original:	J:162138 Takizawa M, et al., Genetic reporter system for oncogenic Igh-Myc translocations in mice. Oncogene. 2010 Jul 15;29(28):4113-20
All:	1 reference(s)