Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Adcy6tm2Yich
Name:	adenylate cyclase 6; targeted mutation 2, Yijuang Chern
MGI ID:	MGI:4459917
Gene:	Adcy6  Location: Chr15:98487854-98507957 bp, - strand  Genetic Position: Chr15, 54.59 cM, cytoband F
Alliance:	Adcy6tm2Yich page

Germline Transmission:	Earliest citation of germline transmission: J:161317
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exons 2 and 3 were replaced a neomycin resistance cassette by homologous recombination. Absence of protein was confirmed by western blot. (J:161317)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy6 Mutation:	49 strains or lines available

Original:	J:161317 Chien CL, et al., Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6). FEBS Lett. 2010 Jul 2;584(13):2883-90
All:	2 reference(s)