Tg(tetO-Gnaq*R183C)1Conk
Transgene Detail
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| Symbol: |
Tg(tetO-Gnaq*R183C)1Conk |
| Name: |
transgene insertion 1, Bruce R Conklin |
| MGI ID: |
MGI:4455195 |
| Synonyms: |
tetO-Gq* |
| Transgene: |
Tg(tetO-Gnaq*R183C)1Conk Location: unknown
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| Alliance: |
Tg(tetO-Gnaq*R183C)1Conk page
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| Transgene Type: |
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Transgenic (Constitutively active, Inducible, Inserted expressed sequence) |
| Inducer: |
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doxycycline/tetracycline |
| Mutation: |
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Insertion
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Mutation details: This transgene contains the tetracycline responsive element (TRE) driving expression, from a minimal promoter, of a mutant guanine nucleotide-binding protein, alpha q polypeptide (alpha q) in which the arginine at amino acid position 183 has been replaced by cysteine (R183C). This constitutively active mutant protein maintains phospholipase C in an active state. It is expressed in the presence of tTA without tetracycline (tet-off) or in the presence of rtTA and tetracycline (tet-on),
(J:94077)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015; |
| All: |
1 reference(s) |
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Analysis Tools
