Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Fos/EGFP)4-1Brth
Name:	transgene insertion 4-1, Alison Barth
MGI ID:	MGI:4443295
Transgene:	Tg(Fos/EGFP)4-1Brth  Location: unknown
Alliance:	Tg(Fos/EGFP)4-1Brth page

Strain of Origin:

(DBA x C57BL/6)F1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: This transgene contains a fusion of the c-fos promoter and the c-fos coding region, including exons and introns, to the coding region for enhanced green fluorescent protein (EGFP) creating a fosGFP C-terminus fusion protein. The gene for EGFP was fused in frame to the last exon, and the poly(A) tail is derived from the IRES (phosphorylated-internal ribosomal entry site)-EGFP. Four lines were established (lines 1-3, 4-1, 5-1, and 6-1) with slightly different levels of expression in the central nervous system. (J:159440)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:159440 Barth AL, et al., Alteration of neuronal firing properties after in vivo experience in a FosGFP transgenic mouse. J Neurosci. 2004 Jul 21;24(29):6466-75
All:	1 reference(s)