Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Slc1a7tm1a(EUCOMM)Hmgu
Name:	solute carrier family 1 (glutamate transporter), member 7; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
MGI ID:	MGI:4436714
Gene:	Slc1a7  Location: Chr4:107825603-107870726 bp, + strand  Genetic Position: Chr4, 50.18 cM
Alliance:	Slc1a7tm1a(EUCOMM)Hmgu page
IMPC:	Slc1a7 gene page

Mutant Cell Line:	HEPD0537_5_G04
Germline Transmission:	Earliest citation of germline transmission: J:165965
Parent Cell Line:	JM8.N4 (ES Cell)
Strain of Origin:	C57BL/6N
Project Collection:	EUCOMM

Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter) Mutation:    Insertion     Vector: L1L2_st0   Mutation details: The L1L2_st0 cassette was inserted at position 107834337 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 107835229. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157065)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Slc1a7 Mutation:	43 strains or lines available

Original:	J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015;
All:	2 reference(s)