Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Bmp4tm4Blh Name: bone morphogenetic protein 4; targeted mutation 4, Brigid L Hogan MGI ID: MGI:3797048 Synonyms: Bmp4loxP Gene: Bmp4  Location: Chr14:46620982-46628126 bp, - strand  Genetic Position: Chr14, 23.95 cM Alliance: Bmp4tm4Blh page

Hindlimb fusion of Bmp4tm4Blh/Bmp4tm4Blh Isl1tm1(cre)Sev/Isl1+ mice Show the 4 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:136636
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted into introns 2 and 4. An frt-flanked neo cassette used for selection was removed by germ line, flp-mediated recombination. (J:136636)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	62 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	14 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmp4 Mutation:	21 strains or lines available

Original:	J:136636 Chang W, et al., Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements. PLoS Genet. 2008 Apr;4(4):e1000050
All:	18 reference(s)