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Stk4tm1Yy
Targeted Allele Detail
Summary
Symbol: Stk4tm1Yy
Name: serine/threonine kinase 4; targeted mutation 1, Yingzi Yang
MGI ID: MGI:4422171
Synonyms: Mst1c
Gene: Stk4  Location: Chr2:163916033-163997444 bp, + strand  Genetic Position: Chr2, 84.6 cM, cytoband H3
Alliance: Stk4tm1Yy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156541
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 4 and an frt flanked neo cassette and second loxP site were inserted downstream of exon 5. (J:156541)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk4 Mutation:  72 strains or lines available
References
Original:  J:156541 Song H, et al., Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1431-6
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory