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Targeted Allele Detail
Symbol: Nr1d1tm1(KOMP)Wtsi
Name: nuclear receptor subfamily 1, group D, member 1; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:4419657
Gene: Nr1d1  Location: Chr11:98658758-98666159 bp, - strand  Genetic Position: Chr11, 62.66 cM
Mutant Cell Lines:  EPD0401_2_A11, EPD0401_2_B10, EPD0401_2_C09, EPD0401_2_C11, EPD0401_2_C12, EPD0401_2_E11, EPD0401_2_E12, EPD0401_2_F09, EPD0401_2_F10, EPD0401_2_G09, EPD0401_2_G10, EPD0401_2_G11, EPD0401_2_G12, EPD0401_2_H10, EPD0401_2_H12
Germline Transmission:  Unknown
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
Mutation detailsThe insertion of the L1L2_Bact_P cassette created a deletion of size 1918 starting at position 98660458 and ending at position 98662376 of Chromosome 11 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Nr1d1 Mutation:  25 strains or lines available
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory