Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(tetO-Fos)1Vsn
Name:	transgene insertion 1, Charles Vinson
MGI ID:	MGI:3795155
Synonyms:	tetA-FOS, TetOp-A-FOS
Transgene:	Tg(tetO-Fos)1Vsn  Location: unknown
Alliance:	Tg(tetO-Fos)1Vsn page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Dominant negative, Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Mutation details: This transgenic construct expresses a high-affinity AP-1 dominant-negative protein (A-FOS) via tetracycline-inducible promoter elements. A-FOS is a chimeric protein containing the c-FOS leucine zipper and a designed acidic protein sequence that replaces the DNA-binding region. (J:112098)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:112098 Gerdes MJ, et al., Activator protein-1 activity regulates epithelial tumor cell identity. Cancer Res. 2006 Aug 1;66(15):7578-88
All:	2 reference(s)