Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Enpp1asj Name: ectonucleotide pyrophosphatase/phosphodiesterase 1; ages with stiffened joints MGI ID: MGI:3785162 Gene: Enpp1  Location: Chr10:24513812-24588057 bp, - strand  Genetic Position: Chr10, 12.26 cM Alliance: Enpp1asj page

Stiffening of the joints in Enpp1asj/Enpp1asj (right) mice, particularly in the forepaws Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This ENU induced mutation was found to be an exon 7 T to A point mutation at position 737, predicted to change a valine to an aspartic acid. (J:174912)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

25 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Enpp1 Mutation:	9 strains or lines available

Original:	J:174912 Harris BS, et al., Ages with stiffened joints, A new mutation in Enpp1. MGI Direct Data Submission. 2011;
All:	18 reference(s)