Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Rspo1tm1Mcch
Name:	R-spondin 1; targeted mutation 1, Marie-Christine Chaboissier
MGI ID:	MGI:3784976
Gene:	Rspo1  Location: Chr4:124880223-124902892 bp, + strand  Genetic Position: Chr4, 57.96 cM
Alliance:	Rspo1tm1Mcch page

Germline Transmission:	Earliest citation of germline transmission: J:133933
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A lacZ gene and neo cassette were inserted into exon 3. The absence of transcript was confirmed by RT-PCR analysis on E13.5 embryo extracts. (J:133933)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rspo1 Mutation:	21 strains or lines available

Original:	J:133933 Chassot AA, et al., Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary. Hum Mol Genet. 2008 May 1;17(9):1264-77
All:	15 reference(s)