About   Help   FAQ
Polr2atm1(CAG-nLacZ)Mrc
Targeted Allele Detail
Summary
Symbol: Polr2atm1(CAG-nLacZ)Mrc
Name: polymerase (RNA) II (DNA directed) polypeptide A; targeted mutation 1, Mario R Capecchi
MGI ID: MGI:3783309
Synonyms: nLacZ, Polr2atm1(ACTB-nLacZ)Mrc
Gene: Polr2a  Location: Chr11:69624823-69649459 bp, - strand  Genetic Position: Chr11, 42.86 cM, cytoband B1-C
Alliance: Polr2atm1(CAG-nLacZ)Mrc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:133338
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA cassette including a CAG promoter (chicken beta-actin with the CMV enhancer) driving the expression of LacZ with a nuclear localization signal was inserted 1 kb downstream of the poly-adenylation signal (details will be published elsewhere). (J:133338)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Polr2a Mutation:  92 strains or lines available
References
Original:  J:133338 Haldar M, et al., Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis. Dev Cell. 2008 Mar;14(3):437-45
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory