Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gt(ROSA)26Sortm1(CAG-ECFP/Venus)Kgwa
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Osami Kanagawa
MGI ID:	MGI:4366503
Synonyms:	Gt(ROSA)26Sortm1Kgwa, ROSA-lox-stop-lox-SCAT3.1
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm1(CAG-ECFP/Venus)Kgwa page

Germline Transmission:	Earliest citation of germline transmission: J:153768
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	(C57BL/6 x DBA/2)F1

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: The CAG-driven SCAT3.1 (caspase-3-sensitive fusion protein) with an upstream floxed STOP cassette was inserted into the locus. SCAT3.1 contains a fusion of ECFP and the Venus EYFP analog connected by a caspase 3 cleavable peptide. Removal of the floxed STOP cassette is required for the expression of the caspase-3-sensitive reporter fusion. (J:153768)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	944 strains or lines available

Original:	J:153768 Tomura M, et al., Time-lapse observation of cellular function with fluorescent probe reveals novel CTL-target cell interactions. Int Immunol. 2009 Oct;21(10):1145-50
All:	1 reference(s)