Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Pnpg
Name:	purine-nucleoside phosphorylase; NP-1G
MGI ID:	MGI:3777975
Synonyms:	Np-1g
Gene:	Pnp  Location: Chr14:51181760-51190869 bp, + strand  Genetic Position: Chr14, 26.31 cM, cytoband B-C1
Alliance:	Pnpg page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This allele was identified in the progeny of a cross between ENU mutagenized C57BL/6J males and C3H/HeHa females. A T to C transition occurred at nucleotide 46 resulting in a W16R amino acid change in the resulting protein. (J:522, J:39328)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pnp Mutation:	29 strains or lines available

Original:	J:522 Snyder FF, Genetic models of purine nucleoside phosphorylase deficiency in the mouse. Adv Exp Med Biol. 1991;309B:137-40
All:	3 reference(s)