Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hprt1tm1Brd
Name:	hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Allan Bradley
MGI ID:	MGI:3776893
Synonyms:	hprttm(rmce1)Brd
Gene:	Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance:	Hprt1tm1Brd page

Germline Transmission:	Earliest citation of germline transmission: J:132633
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A puromycin resistance cassette flanked by loxP and lox5-11 sites was inserted into intron 2. This allele is an RMCE ready locus. (J:132633)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:	1274 strains or lines available

Original:	J:132633 Prosser HM, et al., Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereocilia. Mol Cell Biol. 2008 Mar;28(5):1702-12
All:	1 reference(s)