Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ldhaa-m5Neu
Name:	lactate dehydrogenase A; mutation 5, Neuherberg
MGI ID:	MGI:3776265
Synonyms:	LDH 1623, Ldh1a5Neu
Gene:	Ldha  Location: Chr7:46491698-46505051 bp, + strand  Genetic Position: Chr7, 30.6 cM
Alliance:	Ldhaa-m5Neu page

Strain of Origin:

(102/El x C3H/El)F1

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU-mutagenesis resulted in a transition of A to G at codon 216 that caused an amino acid substitution of a glycine for a glutamic acid at position 216 (E216G). Enzyme activity is 85% of wild-type in homozygous mice. (J:22177) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ldha Mutation:	34 strains or lines available

Original:	J:506 Merkle S, et al., Characterization of two electrophoretic lactate dehydrogenase-A mutants in Mus musculus. Biochem Genet. 1992 Feb;30(1-2):49-59
All:	4 reference(s)