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Mtf1tm1e(KOMP)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Mtf1tm1e(KOMP)Wtsi
Name: metal response element binding transcription factor 1; targeted mutation 1e, Wellcome Trust Sanger Institute
MGI ID: MGI:4363268
Gene: Mtf1  Location: Chr4:124802549-124849800 bp, + strand  Genetic Position: Chr4, 57.91 cM, cytoband D1
Mutation
origin
Mutant Cell Lines:  EPD0025_1_A11, EPD0025_1_A12, EPD0025_1_B10, EPD0025_1_B12, EPD0025_1_C10, EPD0025_1_C11, EPD0025_1_E12, EPD0025_1_F10, EPD0025_1_F12
Germline Transmission:  Unknown
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt0
 
Mutation detailsThe L1L2_gt0 cassette was inserted at position 124819771 of Chromosome 4 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:148605, J:173534)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Mtf1 Mutation:  11 strains or lines available
References
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory