Klf6tm1Fjs
Targeted Allele Detail
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Symbol: |
Klf6tm1Fjs |
Name: |
Kruppel-like transcription factor 6; targeted mutation 1, Frederic J de Sauvage |
MGI ID: |
MGI:4361337 |
Synonyms: |
Klf6f |
Gene: |
Klf6 Location: Chr13:5911488-5920392 bp, + strand Genetic Position: Chr13, 2.94 cM, cytoband A1
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Alliance: |
Klf6tm1Fjs page
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Abnormality in ductal branching in the Klf6tm1Fjs/Klf6tm1Fjs Nkx3-1tm3(cre)Mms/Nkx3-1+ prostate epithelium
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:153183
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A floxed, reverse orientation neo cassette was inserted into intron 1 and a single laxP site was inserted into intron 3 via homologous recombination.
(J:153183)
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Generation of the Klf6tm1Fjs allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Klf6 Mutation: |
15 strains or lines available
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Original: |
J:153183 Leow CC, et al., Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway. J Biol Chem. 2009 Jul 31;284(31):21057-65 |
All: |
13 reference(s) |
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