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Wnt2btm1Eem
Targeted Allele Detail
Summary
Symbol: Wnt2btm1Eem
Name: wingless-type MMTV integration site family, member 2B; targeted mutation 1, Edward E Morrisey
MGI ID: MGI:4361156
Gene: Wnt2b  Location: Chr3:104852588-104869237 bp, - strand  Genetic Position: Chr3, 45.88 cM
Alliance: Wnt2btm1Eem page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153098
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 5' loxP site was inserted downstream of exon 3. (J:153098)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt2b Mutation:  22 strains or lines available
References
Original:  J:153098 Goss AM, et al., Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell. 2009 Aug;17(2):290-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory