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Dact1tm1Bnrc
Targeted Allele Detail
Summary
Symbol: Dact1tm1Bnrc
Name: dishevelled-binding antagonist of beta-catenin 1; targeted mutation 1, Benjamin N R Cheyette
MGI ID: MGI:4360071
Synonyms: Dact1neo flox
Gene: Dact1  Location: Chr12:71356658-71366881 bp, + strand  Genetic Position: Chr12, 29.39 cM
Alliance: Dact1tm1Bnrc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152701
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neomycin resistance cassette was inserted upstream of exon 2 and exon 2 was floxed via homologous recombination. (J:152701)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dact1 Mutation:  21 strains or lines available
References
Original:  J:152701 Suriben R, et al., Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak. Nat Genet. 2009 Sep;41(9):977-85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory