Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	mt-Atp8m1
Name:	mitochondrially encoded ATP synthase 8; mutation 1
MGI ID:	MGI:4355536
Synonyms:	mt-Atp8FVB/NJ
Gene:	mt-Atp8  Location: ChrMT:7766-7969 bp, + strand  Genetic Position: ChrMT, Syntenic
Alliance:	mt-Atp8m1 page

Strain of Origin:

FVB/NJ

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: A G-to-T transversion is located at nucleotide 7778 resulting in an aspartic acid to tyrosine substitution in the fifth amino acid of the conserved N-terminus of the protein (p.D5Y). This substitution has been reported in the FVB/NJ strain. (J:143901)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 5 strains available      Cell Lines: 0 lines available
Carrying any mt-Atp8 Mutation:	5 strains or lines available

Original:	J:143901 Yu X, et al., Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains. Genome Res. 2009 Jan;19(1):159-65
All:	7 reference(s)