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Gt(ROSA)26Sortm10(RNAi:P2rx7)Rkuhn
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm10(RNAi:P2rx7)Rkuhn
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 10, Ralf Kuhn
MGI ID: MGI:4353634
Synonyms: shP2RX7
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm10(RNAi:P2rx7)Rkuhn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151155
Parent Cell Line:  IDG3.2 (ES Cell)
Strain of Origin:  (C57BL/6J x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
  Gt(ROSA)26Sortm10(RNAi:P2rx7)Rkuhn involves 1 genes/genome features (P2rx7) View all
 
Mutation details: Using RMCE, an inserted hygro cassette was replaced with a neo cassette and a short hairpin RNA driven by the human U6 promoter that targets P2rx7. (J:151155)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  944 strains or lines available
References
Original:  J:151155 Delic S, et al., Genetic mouse models for behavioral analysis through transgenic RNAi technology. Genes Brain Behav. 2008 Oct;7(7):821-30
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory