Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Esrrgtm1Rev
Name:	estrogen-related receptor gamma; targeted mutation 1, Ronald M Evans
MGI ID:	MGI:3771320
Synonyms:	ERRgamma S-strain, Esrrg-
Gene:	Esrrg  Location: Chr1:187340988-187947082 bp, + strand  Genetic Position: Chr1, 91.83 cM, cytoband H5
Alliance:	Esrrgtm1Rev page

Germline Transmission:	Earliest citation of germline transmission: J:129851
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A lacZ-neo cassette was inserted into exon 2 deleting the portion that encodes the DNA binding domain. The insertion produces a frame shift in the case of alternative splicing. The absence of a transcript and protein product was confirmed by RT-PCR and immunohistochemistry. (J:129851)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	25 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Esrrg Mutation:	32 strains or lines available

Original:	J:129851 Alaynick WA, et al., ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart. Cell Metab. 2007 Jul;6(1):13-24
All:	8 reference(s)