Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Ckm-Pah)15Mes
Name:	transgene insertion 15, Albee Messing
MGI ID:	MGI:3769421
Synonyms:	Tg(Mck-Pah)15Mes, TgN(MCKPah)15Mes
Transgene:	Tg(Ckm-Pah)15Mes  Location: unknown
Alliance:	Tg(Ckm-Pah)15Mes page

Strain of Origin:

(C57BL/6J x SJL)F2

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Ckm-Pah)15Mes expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Pah (MGI:97473)   Mutation details: Mouse liver Pah cDNA was fused to a 3300 bp DNA sequence from the 5' regulatory regions of the mouse muscle creatine kinase (MCK) gene. This line carries approximately 5-10 copies of the transgene as a tandem repeat. PAH activity was detected in tissue homogenates from liver and kidney and also in both skeletal and cardiac muscle. (J:47853)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:47853 Harding CO, et al., Metabolic engineering as therapy for inborn errors of metabolism--development of mice with phenylalanine hydroxylase expression in muscle. Gene Ther. 1998 May;5(5):677-83
All:	1 reference(s)