Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Twist1tm2.1Bhr
Name:	twist basic helix-loop-helix transcription factor 1; targeted mutation 2.1, Richard R Behringer
MGI ID:	MGI:3768519
Synonyms:	Twist1deltaEx1
Gene:	Twist1  Location: Chr12:34007670-34009828 bp, + strand  Genetic Position: Chr12, 14.81 cM, cytoband B-C1
Alliance:	Twist1tm2.1Bhr page

Germline Transmission:	Earliest citation of germline transmission: J:128714
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     The open reading frame was removed by cre-mediated recombination to create a null allele. (J:128714)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	37 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Twist1 Mutation:	18 strains or lines available

Original:	J:128714 Chen YT, et al., Generation of a Twist1 conditional null allele in the mouse. Genesis. 2007 Sep;45(9):588-92
All:	3 reference(s)