Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ppargc1btm1Avp
Name:	peroxisome proliferative activated receptor, gamma, coactivator 1 beta; targeted mutation 1, Antonio Vidal-Pulg
MGI ID:	MGI:3757704
Gene:	Ppargc1b  Location: Chr18:61431207-61533502 bp, - strand  Genetic Position: Chr18, 34.41 cM
Alliance:	Ppargc1btm1Avp page

Germline Transmission:	Earliest citation of germline transmission: J:116167
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed PGK-neo cassette was inserted into intron 3 and an additional loxP site downstream of exon 5. (J:116167)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppargc1b Mutation:	56 strains or lines available

Original:	J:116167 Lelliott CJ, et al., Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS Biol. 2006 Nov;4(11):e369
All:	1 reference(s)