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Slc14a2Tn(pb-ZG-s)1.1Mrc
Transposon induced Allele Detail
Summary
Symbol: Slc14a2Tn(pb-ZG-s)1.1Mrc
Name: solute carrier family 14 (urea transporter), member 2; transposon insertion 1.1, Mario R Capecchi
MGI ID: MGI:3719412
Gene: Slc14a2  Location: Chr18:78189363-78640157 bp, - strand  Genetic Position: Chr18, 52.53 cM
Alliance: Slc14a2Tn(pb-ZG-s)1.1Mrc page
Mutation
origin
Strain of Origin:  Not Applicable
Mutation
description
Allele Type:    Transposon induced (Reporter)
Mutation:    Transposon insertion
 
Mutation detailspiggyBac transposase mediated recombination inserted the ZG-s transposable gene-trap vector into this gene. The gene-trap vector consists of piggyBac terminal repeats and internal sequence with all potential splice donor sites removed flanking a loxP site, a splice acceptor site, an IRES-beta-galactosidase-polyA cassette, an FRT site, a CAG-eGFP-polyA cassette, a loxP site, a lox5171 site, and an FRT site. Flp-mediated recombination removes the eGFP cassette. Cre-mediated recombination removes the splice acceptor and beta-galactosidase cassette restoring gene expression. (J:123007)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc14a2 Mutation:  53 strains or lines available
References
Original:  J:123007 Wu S, et al., Toward simpler and faster genome-wide mutagenesis in mice. Nat Genet. 2007 Jul;39(7):922-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory