Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Pou1f1-cre,-ALPP)1Xdfu
Name:	transgene insertion 1, Xiang-Dong Fu
MGI ID:	MGI:3719216
Synonyms:	Pit-1-Cre/hpAP
Transgene:	Tg(Pou1f1-cre,-ALPP)1Xdfu  Location: unknown
Alliance:	Tg(Pou1f1-cre,-ALPP)1Xdfu page

Strain of Origin:

Not Applicable

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Pou1f1-cre,-ALPP)1Xdfu expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Pou1f1   Mutation details: This transgene was designed to express cre recombinase during pituitary developmental stages starting at e13.5, using a 15.5 kb POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) promoter. An IRES separated the cre cDNA from the human placenta alkaline phosphatase gene and polyA signal. The promoter is capable of driving expression in all three cell lineages: the somatotrophs, lactotrophs and thyrotrophs. (J:123618)

Activity:	Tissue activity of this recombinase allele
Driver:	Pou1f1 (species not specified) Summary of all recombinase alleles driven by Pou1f1.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:123618 Xiao R, et al., Splicing regulator SC35 is essential for genomic stability and cell proliferation during mammalian organogenesis. Mol Cell Biol. 2007 Aug;27(15):5393-402
All:	1 reference(s)