Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tbx3tm1.1(cre)Vmc
Name:	T-box 3; targeted mutation 1.1, Vincent M Christoffels
MGI ID:	MGI:3710254
Synonyms:	Tbx3cre
Gene:	Tbx3  Location: Chr5:119808734-119822789 bp, + strand  Genetic Position: Chr5, 60.34 cM
Alliance:	Tbx3tm1.1(cre)Vmc page

Germline Transmission:	Earliest citation of germline transmission: J:121230
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Tbx3tm1.1(cre)Vmc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tbx3 (MGI:98495)   Mutation details: A cre recombinase cDNA was inserted upstream to replace the first 3 codons in exon 1. A floxed neo was removed by Flp recombinase in the germline. (J:121230)

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx3 (mouse) Summary of all recombinase alleles driven by Tbx3. Alliance mouse Tbx3 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	3 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx3 Mutation:	49 strains or lines available

Original:	J:121230 Hoogaars WM, et al., Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria. Genes Dev. 2007 May 1;21(9):1098-112
All:	8 reference(s)