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Smad2tm1.3Epb
Targeted Allele Detail
Summary
Symbol: Smad2tm1.3Epb
Name: SMAD family member 2; targeted mutation 1.3, Erwin P Bottinger
MGI ID: MGI:3703162
Synonyms: Smad2deltaex2
Gene: Smad2  Location: Chr18:76374651-76444034 bp, + strand  Genetic Position: Chr18, 51.42 cM
Alliance: Smad2tm1.3Epb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119642
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe locus contains a single loxP site in place of exon 2 following the cre mediated deletion of a pgk-neo and exon 2. (J:119642)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad2 Mutation:  50 strains or lines available
References
Original:  J:119642 Ju W, et al., Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation. Mol Cell Biol. 2006 Jan;26(2):654-67
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory