Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Smad9tm1Rob
Name:	SMAD family member 9; targeted mutation 1, Elizabeth J Robertson
MGI ID:	MGI:3701868
Synonyms:	Smad8.LacZ
Gene:	Smad9  Location: Chr3:54663003-54708678 bp, + strand  Genetic Position: Chr3, 25.62 cM, cytoband D
Alliance:	Smad9tm1Rob page

Germline Transmission:	Earliest citation of germline transmission: J:119296
Parent Cell Line:	CCE/EK.CCE (ES Cell)
Strain of Origin:	129S/SvEv-Gpi1c

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A LacZ cassette was inserted into the AUG-containing exon 2, disrupting endogenous coding sequence and creating a null allele. Beta-galactosidase is expressed from this allele under the control of the endogenous promoter. (J:119296)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

65 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Smad9 Mutation:	32 strains or lines available

Original:	J:119296 Arnold SJ, et al., Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol. 2006 Aug 1;296(1):104-18
All:	3 reference(s)