Ighmtm2Bgmn
Targeted Allele Detail
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| Symbol: |
Ighmtm2Bgmn |
| Name: |
immunoglobulin heavy constant mu; targeted mutation 2, Marianne Bruggeman |
| MGI ID: |
MGI:3701076 |
| Synonyms: |
mulox |
| Gene: |
Ighm Location: Chr12:113382446-113386350 bp, - strand Genetic Position: Chr12, 62.1 cM, cytoband F1-2
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| Alliance: |
Ighmtm2Bgmn page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:118453
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| Parent Cell Line: |
ZX3 (ES Cell)
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| Strain of Origin: |
129/Sv
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| Allele Type: |
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Targeted (Conditional ready, Modified regulatory region, No functional change) |
| Mutation: |
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Insertion
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Mutation details: A puromycin resistance gene cassette with a 5' loxP site was inserted into exon 1 and 2 of the Igh Cmu gene segment, deleting 330bp of 3' of exon 1, intron 1 and 5' of exon 2. This insertion was done in ES cells that already had a neo cassette with a 3' loxP site in the alpha 3' enhancer of Igh Calpha (Rr151).
(J:118453)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Ighm Mutation: |
55 strains or lines available
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| Original: |
J:118453 Ren L, et al., Silencing of the immunoglobulin heavy chain locus by removal of all eight constant-region genes in a 200-kb region. Genomics. 2004 Oct;84(4):686-95 |
| All: |
1 reference(s) |
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Analysis Tools
